BTKGC - CHLOROMYCETIN OPHTHALMIC

Product Identification

Product ID:CHLOROMYCETIN OPHTHALMIC
MSDS Date:06/06/1991
FSC:6505
NIIN:00F034800
MSDS Number: BTKGC

Responsible Party
PARK-DAVIS DIV OF WARNER LAMBERT LTD
201 TABOR ROAD
MORRIS PLAINS, NJ 07950-2614
US

Emergency Phone: 201-540-2000

Info Phone: 201-540-2000

Preparer: ROY MUELLER

Cage: 2T119

Contractor
PARK-DAVIS DIV OF WARNER LAMBERT LTD
MORRIS PLAINS, NJ 07950-2614 US

Telephone: 201-540-2000

Cage: 2T119

Ingredients

CHLORAMPHENICOL (CHLOROMYCETIN)

CAS: 56-75-7

RTECS: AB6825000


BORIC ACID

CAS: 10043-35-3

RTECS: ED4550000

Hazards

LD50 LC50 Mixture:SEE SUPPLEMENTAL DATA FOR LD50'S
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:YES OSHA:NO
Health Hazards Acute and Chronic:ADVERSE REACTIONS FOLLOWING THE
THEREPUTIC USE OF CHLORAMPHENICOL INCLUDE BONE MARROW DEPRESSION,
SERIOUS TO FATAL BLOOD DYSCRASIAS, G/I DISTURBANCES AND CNS
DISTURBANCES. MARROW DEPRESSION CAN BE REV ERSABLE OR IRREVERSABLE.
Explanation of Carcinogenicity:CHLORAMPHENICAL PRESENT IN THIS PRODUCT
IS LISTED BY IARC AS A POSSIBLE CARCINOGEN.
Effects of Overexposure:MILD SKIN IRRITATION OR SENSITIZATION (MACULAR
RASHES) WERE THE ONLY SYMPTOMS REPORTED.
Medical Cond Aggravated by Exposure:NO INFORMATION GIVEN ON MSDS BY
MFR.

First Aid

First Aid:EYE:FLUSH WITH WATER FOR 15 MINUTES. IF IRRITATION PERSISTS,
GET MEDICAL ATTENTION. SKIN:WASH WITH SOAP & WATER UNTIL FREE OF
RESIDUE. INGESTION:GET IMMEDIATE MEDICAL ATTENTION.
INHALATION:REMOVE TO FRESH AIR. GET MEDICAL ATTENTION.

Fire Fighting

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, FOAM, OR DRY CHEMICAL.
Fire Fighting Procedures:USE APPROVED SELF CONTAINED BREATHING
APPARATUS.
Unusual Fire/Explosion Hazard:NONE

Accidental Release

Spill Release Procedures:WIPE OR MOP UP AND PLACE IN A CONTAINER FOR
DISPOSAL. FLUSH RESIDUE AWAY WITH WATER.
Neutralizing Agent:NO INFORMATION GIVEN ON MSDS BY MFR.

Handling

Handling and Storage Precautions:STORE AS STATED ON LABEL. HANDLE IN
SUCH A WAY AS TO AVOID SKIN AND EYE CONTACT. SHOULD CONTACT OCCUR,
WASH CONTAMINATED SKIN PROMPTLY.
Other Precautions:HANDLE IN A MANNER DESIGNED TO MINIMIZE DUST
GENERATION. KEEP OUT OF REACH OF CHILDREN.

Exposure Controls

Respiratory Protection:NO INFORMATION GIVEN ON MSDS BY MFR.
Ventilation:NO INFORMATION GIVEN ON MSDS BY MFR.
Protective Gloves:NO INFORMATION GIVEN ON MSDS BY MFR.
Eye Protection:NO INFORMATION GIVEN ON MSDS BY MFR.
Other Protective Equipment:NO INFORMATION GIVEN ON MSDS BY MFR.
Work Hygienic Practices:MFR: ? HMIS:USE GOOD CHEMICAL HYGIENE
PRACTICE. AVOID UNNECESSARY CONTACT. WASH THOROUGHLY BEFORE EATING
OR DRINKING.
Supplemental Safety and Health
THIS MEDICINE IS USED AS ANTIBIOTIC, MINIMAL OCCUPATIONAL HAZARD IS
INVOLVED. LD50 (ORAL RAT) IS 2500 MG/KG FOR CHLORAMPHENICOL.
LD50 (ORAL RAT) IS 2660 MG/KG FOR BORIC ACID.

Chemical Properties

HCC:N1
NRC/State Lic Num:NONE
Spec Gravity:1.01
pH:N/D
Solubility in Water:SLIGHTLY SOLUBLE
Appearance and Odor:WHITE TO OFF-WHITE POWDER (FOR RECONSTITUTION);
ODOR: NO DATA FOUND

Stability

Stability Indicator/Materials to Avoid:YES
NO INFORMATION GIVEN ON MSDS BY MFR.
Stability Condition to Avoid:UNDER LABELED STORAGE CONDITIONS, THIS
PRODUCT IS STABLE AND HAZARDOUS POLYMERIZATION SHOULD NOT OCCUR.
Hazardous Decomposition Products:OXIDES OF CARBON AND NITROGEN.
Conditions to Avoid Polymerization:WILL NOT OCCUR

Disposal

Waste Disposal Methods:DISPOSE OF I/A/W FEDERAL, STATE & LOCAL
REGULATIONS OR AUTHORITY HAVING JURISDICTION. INCINERATION IN A
PERMITTED INCINERATOR IS THE PREFERRED DISPOSAL METHOD.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.